SCHEMBL475749

SCHEMBL475749

CC(C)(C)OC(=O)N1CCC(F)(F)C1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
EPHX2 P34913 1/20 0.43
CYP11B2 P19099 1/20 0.41
USP30 Q70CQ3 2/20 0.41
HPGD P15428 1/20 0.41
RORC P51449 3/20 0.40
SCD5 Q86SK9 1/20 0.40
HDAC2 Q92769 1/20 0.40
TSHR P16473 2/20 0.40
ALOX15 P16050 1/20 0.40
RECQL P46063 1/20 0.39
DPP4 P27487 1/20 0.39
DPP7 Q9UHL4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1262593 0.90 HPGD (0.45) USP2SMN1; SMN2EPHX2CYP11B2USP30
SCHEMBL6228410 0.89 USP2 (0.55) USP2SMN1; SMN2EPHX2HPGDTSHR
SCHEMBL9948317 0.88 HPGD (0.48) USP2SMN1; SMN2EPHX2CYP11B2USP30
SCHEMBL12384327 0.85 USP2 (0.48) USP2SMN1; SMN2EPHX2HPGDRECQL
SCHEMBL16590451 0.84 USP2 (0.46) USP2SMN1; SMN2EPHX2CYP11B2USP30
SCHEMBL30254327 0.84 USP2 (0.46) USP2SMN1; SMN2EPHX2CYP11B2USP30
SCHEMBL12445300 0.84 USP2 (0.46) USP2SMN1; SMN2EPHX2CYP11B2USP30
SCHEMBL25341405 0.83 USP2 (0.45) USP2SMN1; SMN2EPHX2CYP11B2USP30
SCHEMBL938773 0.83 HPGD (0.49) USP2SMN1; SMN2EPHX2HPGDTSHR
SCHEMBL21811041 0.83 USP2 (0.45) USP2SMN1; SMN2EPHX2CYP11B2USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071471-A Heterocyclic compounds 武田药品工业株式会社 2026-05-22 CN disclosed
CN-122010946-A Heterocyclic compounds 武田药品工业株式会社 2026-05-12 CN disclosed
CN-122010945-A Heterocyclic compounds 武田药品工业株式会社 2026-05-12 CN disclosed
CN-114716381-B Compounds useful as kinase inhibitors 洛克索肿瘤学股份有限公司 2025-03-11 CN disclosed
CN-114605327-B Compounds useful as kinase inhibitors 洛克索肿瘤学股份有限公司 2025-03-11 CN disclosed
CN-114573510-B Compounds useful as kinase inhibitors 洛克索肿瘤学股份有限公司 2025-02-25 CN disclosed
CN-114591223-B Beta-lactamase inhibitor compounds 恩塔西斯治疗有限公司 2025-01-24 CN disclosed
CN-114591242-B Compounds useful as kinase inhibitors 洛克索肿瘤学股份有限公司 2025-01-07 CN disclosed
CN-119110802-A Heterocyclic derivatives substituted with a middle or macrocyclic benzyl group and related uses 森特萨制药(英国)有限公司 2024-12-10 CN disclosed
CN-114634447-B Compounds useful as kinase inhibitors 洛克索肿瘤学股份有限公司 2024-11-15 CN disclosed
US-20050043299-A1 Inhibitors of dipeptidyl peptidase iv FERRING B. V. 2005-02-24 US disclosed
US-20040235752-A1 3-fluoro-pyrrolidines as antidiabetic agents FERRING B.V. (NL) 2004-11-25 US disclosed
US-20040186134-A1 Sulfonamide lactam inhibitors of FXa and method O'CONNOR STEPHEN P (US) 2004-09-23 US disclosed
EP-1446116-A1 INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FERRING B.V. (NL) 2004-08-18 EP disclosed
EP-1399154-A1 3-FLUORO-PYRROLIDINES AS ANTIDIABETIC AGENTS Ferring BV (NL) 2004-03-24 EP disclosed
EP-1358178-A2 SULFONAMIDE LACTAM INHIBITORS OF FACTOR XA Bristol-Myers Squibb Company (US) 2003-11-05 EP disclosed
WO-2003035057-A1 INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FERRING B.V. (NL) 2003-05-01 WO disclosed
US-6555542-B1 Factor Xa (FXa); useful as anticoagulants in the treatment of cardiovascular diseases associated with thrombosis BRISTOL-MYERS SQUIBB COMPANY 2003-04-29 US disclosed
WO-2003000250-A1 3-FLUORO-PYRROLIDINES AS ANTIDIABETIC AGENTS FERRING BV (NL) 2003-01-03 WO disclosed
WO-2002060894-A2 SULFONAMIDE LACTAM INHIBITORS OF FACTOR XA BRISTOL-MYERS SQUIBB COMPANY (US) 2002-08-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235752-A1 3-fluoro-pyrrolidines as antidiabetic agents DPP4, DPP7, DPP3 USP2 2530/4885SMN1; SMN2 4450/4885EPHX2 2439/4885
US-20040186134-A1 Sulfonamide lactam inhibitors of FXa and method STS, SULT1E1, F8 USP2 2612/4885SMN1; SMN2 2767/4885EPHX2 4184/4885
US-20050043299-A1 Inhibitors of dipeptidyl peptidase iv DPP4, DPP9, DPP3 USP2 309/4885SMN1; SMN2 3159/4885EPHX2 1088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.