SCHEMBL4757491

SCHEMBL4757491

CC1(C)OB(c2cccc(-c3cccc(-c4cccc(C=O)c4)c3)c2)OC1(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 10/20 0.45
LPL P06858 9/20 0.45
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
BRD4 O60885 1/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
CA12 O43570 2/20 0.40
ALDH1A1 P00352 1/20 0.39
P4HB P07237 1/20 0.37
CDK8 P49336 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020207 0.92 LIPG (0.48) LIPGLPLTRIM24TRIM33BRD4
SCHEMBL31390229 0.92 LIPG (0.48) LIPGLPLTRIM24TRIM33BRD4
SCHEMBL20023287 0.86 LIPG (0.58) LIPGLPLCA1CA2CA9
SCHEMBL31456345 0.86 LIPG (0.58) LIPGLPLCA1CA2CA9
SCHEMBL31456342 0.86 LIPG (0.58) LIPGLPLCA1CA2CA9
SCHEMBL3797726 0.85 LIPG (0.40) LIPGLPLTRIM24TRIM33BRD4
SCHEMBL15495620 0.84 LIPG (0.56) LIPGLPLCA1CA2CA9
SCHEMBL806784 0.84 LIPG (0.60) LIPGLPLCA1CA2CA9
SCHEMBL26145170 0.82 LIPG (0.45) LIPGLPLP4HBIRAK4
SCHEMBL20320244 0.81 LIPG (0.52) LIPGLPLTRIM24TRIM33BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9065062-B2 Cross-linkable iridium complexes and organic light-emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2015-06-23 US disclosed
US-9065062-B2 Cross-linkable iridium complexes and organic light-emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2015-06-23 US disclosed
US-20120107989-A1 CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME UNIVERSAL DISPLAY CORPORATION 2012-05-03 US disclosed
US-20120107989-A1 CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME UNIVERSAL DISPLAY CORPORATION 2012-05-03 US disclosed
US-8119255-B2 First and second electrode; a first organic layer between the electrodes; the first organic layer is a non-electroluminescent, cross-linked metal complex; and a second organic layer is an emissive electroluminescent organic material UNIVERSAL DISPLAY CORPORATION (US) 2012-02-21 US disclosed
US-8119255-B2 First and second electrode; a first organic layer between the electrodes; the first organic layer is a non-electroluminescent, cross-linked metal complex; and a second organic layer is an emissive electroluminescent organic material UNIVERSAL DISPLAY CORPORATION (US) 2012-02-21 US disclosed
US-20080220265-A1 Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same UNIVERSAL DISPLAY CORPORATION (US) 2008-09-11 US disclosed
US-20080220265-A1 Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same UNIVERSAL DISPLAY CORPORATION (US) 2008-09-11 US disclosed
WO-2008073440-A2 CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2008-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080220265-A1 Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same MTCL3, LIG4, L1CAM LIPG 2935/4885LPL 3274/4885TRIM24 808/4885
US-20120107989-A1 CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME MTCL3, LIG4, L1CAM LIPG 2935/4885LPL 3274/4885TRIM24 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.