Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | JAK1 | P23458 | 3/20 | 0.40 |
| ▸ | TYK2 | P29597 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 3/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2694477 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1DPP4DPP8 | |
| SCHEMBL2694481 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1DPP4DPP8 | |
| SCHEMBL2694479 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1DPP4DPP8 | |
| SCHEMBL4898809 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL2694917 | 0.87 | DPP4 (0.59) | DPP4DPP8DPP9DPP7PREP | |
| Trifluoroacetic Acid SCHEMBL2694915 | 0.87 | DPP4 (0.59) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL16718810 | 0.87 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1DPP4DPP8 | |
| SCHEMBL22754620 | 0.82 | JAK1 (0.46) | KDM4EALDH1A1L3MBTL1DPP4DPP8 | |
| SCHEMBL29940306 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1DPP4DPP8 | |
| SCHEMBL16478649 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1GPR119CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |