Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | ALPI | P09923 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | XIAP | P98170 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL6065563 | 1.00 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL6585990 | 0.98 | SLC7A5 (0.75) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL2311858 | 0.98 | SLC7A5 (0.75) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL1798938 | 0.98 | SLC7A5 (0.75) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL28027026 | 0.89 | SLC7A5 (0.75) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL7741736 | 0.89 | SLC7A5 (0.79) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL5200313 | 0.89 | SLC7A5 (0.79) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL7321619 | 0.87 | SLC7A5 (0.76) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL1908048 | 0.87 | SLC7A5 (0.89) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL28900255 | 0.87 | SLC7A5 (0.89) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| EP-1636164-A2 | PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION | CADILA HEALTHCARE LTD. (IN) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005019152-A2 | PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION | CADILA HEALTHCARE LIMITED (IN) | 2005-03-03 | — | — | WO | disclosed |