Tyrosine

Tyrosine

SCHEMBL1798938

N[C@H](Cc1ccc(O)cc1)C(=O)O.c1ccc2c(c1)C2

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.75
PTGS1 P23219 2/20 0.64
ALPI P09923 1/20 0.64
PKM P14618 1/20 0.64
XIAP P98170 1/20 0.64
HDAC8 Q9BY41 5/20 0.61
KDM4E B2RXH2 1/20 0.51
USP2 O75604 1/20 0.51
EGFR P00533 1/20 0.51
LCK P06239 1/20 0.51
FYN P06241 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
ALOX15 P16050 1/20 0.51
HTR2A P28223 1/20 0.51
PTGS2 P35354 1/20 0.51
RECQL P46063 1/20 0.51
HIF1A Q16665 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
GRIA2 P42262 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL2311858 1.00 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL6585990 1.00 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL4757537 0.98 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL6065563 0.98 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28027026 0.91 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL5200313 0.90 SLC7A5 (0.79) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL7741736 0.90 SLC7A5 (0.79) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL7321619 0.89 SLC7A5 (0.76) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL133206 0.89 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1908049 0.89 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4417221-A2 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS Tyndall Formulation Services, LLC (US) 2024-08-21 EP claimed
CN-115135694-B Polymeric excipients for drug delivery applications 廷德尔配方服务有限责任公司 2024-03-15 CN claimed
EP-4087543-B1 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS TYNDALL FORMULATION SERVICES LLC (US) 2024-03-06 EP claimed
US-11891482-B2 Polymer excipients for drug delivery applications Tyndall Formulation Services, LLC (US) 2024-02-06 US claimed
US-20230382949-A1 LINEAR APELIN RECEPTOR AGONISTS HEPTARES THERAPEUTICS LIMITED (GB) 2023-11-30 US claimed
CN-116730969-A Beta-lapachone-amino acid conjugate, and preparation method and application thereof 中国药科大学 2023-09-12 CN claimed
CN-116710469-A Linear Apelin receptor agonists 赫帕雷斯治疗有限公司 2023-09-05 CN claimed
EP-4087543-A1 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS Tyndall Formulation Services, LLC (US) 2022-11-16 EP claimed
CN-115135694-A Polymeric excipients for drug delivery applications 廷德尔配方服务有限责任公司 2022-09-30 CN claimed
US-20220251296-A1 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS Tyndall Formulation Services, LLC 2022-08-11 US claimed
US-11286344-B2 Polymer excipients for drug delivery applications Tyndall Formulation Services, LLC (US) 2022-03-29 US claimed
WO-2021141603-A1 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS Tyndall Formulation Services, LLC (US) 2021-07-15 WO claimed
US-20210214496-A1 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS Tyndall Formulation Services, LLC 2021-07-15 US claimed
CN-102503850-A Hydroxyl-contained N-acylamino acid and preparation method thereof UNIV TIANJIN 2012-06-20 CN claimed
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ZEALAND PHARMA A/S (DK) 2024-09-03 US disclosed
EP-4417221-A2 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS Tyndall Formulation Services, LLC (US) 2024-08-21 EP disclosed
CN-116730969-B Beta-lapachone-amino acid conjugate, and preparation method and application thereof 中国药科大学 2024-04-19 CN disclosed
EP-1636164-A2 PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION CADILA HEALTHCARE LTD. (IN) 2006-03-22 EP disclosed
WO-2005019152-A2 PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION CADILA HEALTHCARE LIMITED (IN) 2005-03-03 WO disclosed
US-4043993-A New pentapeptides and methods for their production PARKE, DAVIS & COMPANY (US) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286344-B2 Polymer excipients for drug delivery applications CLTB, ACTB, TNNC1 SLC7A5 20/4885PTGS1 3544/4885ALPI 1545/4885
US-20220251296-A1 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS CLTB, ACTB, TNNC1 SLC7A5 20/4885PTGS1 3544/4885ALPI 1545/4885
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ITGB7, ITGB4, ITGA4 SLC7A5 2076/4885PTGS1 4545/4885ALPI 3864/4885
US-11891482-B2 Polymer excipients for drug delivery applications CLTB, ACTB, TNNC1 SLC7A5 20/4885PTGS1 3544/4885ALPI 1545/4885
US-20210214496-A1 POLYMER EXCIPIENTS FOR DRUG DELIVERY APPLICATIONS CLTB, ACTB, TNNC1 SLC7A5 20/4885PTGS1 3544/4885ALPI 1545/4885
US-20230382949-A1 LINEAR APELIN RECEPTOR AGONISTS APLNR, MTNR1A, EDNRA SLC7A5 2228/4885PTGS1 1020/4885ALPI 2143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.