Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476239 | 0.98 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| Bromide SCHEMBL11522116 | 0.96 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| Sulfuric Acid SCHEMBL29013316 | 0.91 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| Sulfuric Acid SCHEMBL29013317 | 0.90 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL16352906 | 0.89 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL2530402 | 0.89 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10609079 | 0.87 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL28703203 | 0.87 | TSHR (0.58) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10882384 | 0.87 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29106980 | 0.86 | TSHR (0.62) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112029320-B | Ceramic powder capable of promoting blood circulation, sterilizing and releasing far infrared rays and application of ceramic powder in diatom ooze water-based paint | 刘鹏 | 2022-09-30 | — | — | CN | claimed |
| CN-114276488-B | Long-chain branch multi-head cationic polyacrylamide and application thereof | 河南博源新材料有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-111909069-B | Degradable quaternary ammonium salt compound and preparation method and application thereof | 安徽启威生物科技有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114276488-A | Long-chain branch multi-head cationic polyacrylamide and application thereof | 河南博源新材料有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-109439034-B | Bi-component diatom ooze water-based paint with zero VOC (volatile organic compounds) emission | 刘鹏 | 2021-05-14 | — | — | CN | claimed |
| CN-112029320-A | Ceramic powder capable of promoting blood circulation, sterilizing and releasing far infrared rays and application of ceramic powder in diatom ooze water-based paint | 刘鹏 | 2020-12-04 | — | — | CN | claimed |
| CN-111909069-A | Degradable quaternary ammonium salt compound and preparation method and application thereof | 安徽启威生物科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-105745188-B | High efficiency rheology modifiers with cationic components and uses thereof | 赫尔克里士公司 | 2019-09-10 | — | — | CN | claimed |
| EP-3055285-A2 | HIGH EFFICIENCY RHEOLOGY MODIFERS WITH CATIONIC COMPOMENTS AND USE THEREOF | Hercules Incorporated (US) | 2016-08-17 | — | — | EP | claimed |
| CN-105745188-A | High efficiency rheology modifiers with cationic components and uses thereof | 赫尔克里士公司 | 2016-07-06 | — | — | CN | claimed |
| CN-105085822-A | Sludge-proof type polycarboxylate water-reducer and normal temperature preparing method thereof | KEZHIJIE NEW MATERIALS GROUP CO LTD | 2015-11-25 | — | — | CN | claimed |
| WO-2015054069-A2 | HIGH EFFICIENCY RHEOLOGY MODIFERS WITH CATIONIC COMPOMENTS AND USE THEREOF | HERCULES INCORPORATED (US) | 2015-04-16 | — | — | WO | claimed |
| US-20150105500-A1 | HIGH EFFICIENCY RHEOLOGY MODIFERS WITH CATIONIC COMPONENTS AND USE THEREOF | AVOCA LLC | 2015-04-16 | — | — | US | claimed |
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | claimed |
| US-7901697-B2 | Synthetic thickeners for cosmetics | LAMBERTI SPA (IT) | 2011-03-08 | — | — | US | claimed |
| US-12630728-B2 | Ink set and recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-19 | — | — | US | disclosed |
| CN-117545826-B | Viscosity index improver, refrigerator oil, and working fluid composition for refrigerator | 三洋化成工业株式会社 | 2026-05-15 | — | — | CN | disclosed |
| US-5334679-A | Polymerizing a quaternized acrylate monomer alone or with a copolymerizable monomer in the presence of a surfactant by suspension polymerization | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| US-5244768-A | Manufacturing process for an electrophotographic toner | FUJI XEROX CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5075197-A | Water based polymer dispersion | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630728-B2 | Ink set and recording method | DOT1L, SET, ALKBH3 | CHRM1 626/4885CHRM3 260/4885CHRM2 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.