Azobenzene

Azobenzene

SCHEMBL475771

O=C(O)O.O=C(O)O.c1ccc(N=Nc2ccccc2)cc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Azobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.75
TRPA1 O75762 1/20 0.68
MEN1 O00255 6/20 0.62
KMT2A Q03164 6/20 0.62
NPC1 O15118 2/20 0.62
MAPT P10636 7/20 0.56
KDM4E B2RXH2 2/20 0.56
MAPK1 P28482 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
HSP90AA1 P07900 1/20 0.56
POLB P06746 1/20 0.56
CYP2D6 P10635 1/20 0.56
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CASP3 P42574 1/20 0.56
SENP8 Q96LD8 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HTT P42858 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azobenzene SCHEMBL9435350 1.00 ALDH1A1 (0.75) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL182577 0.90 ALDH1A1 (0.92) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL182578 0.90 ALDH1A1 (0.92) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL23630837 0.88 ALDH1A1 (0.67) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL29154401 0.88 ALDH1A1 (0.67) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL28504207 0.88 ALDH1A1 (0.67) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL6703357 0.87 ALDH1A1 (1.00) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL32032 0.87 ALDH1A1 (1.00) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL11124477 0.87 ALDH1A1 (1.00) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL6562161 0.87 ALDH1A1 (1.00) ALDH1A1TRPA1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3357929-B1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES CENTRE NAT RECH SCIENT (FR) 2020-06-17 EP claimed
EP-2716360-B9 METHOD FOR PREPARING POROUS ORGANIC-INORGANIC HYBRID MATERIALS KOREA RES INST CHEMICAL TECH (KR) 2019-03-27 EP claimed
EP-2716360-B1 METHOD FOR PREPARING POROUS ORGANIC-INORGANIC HYBRID MATERIALS KOREA RES INST CHEMICAL TECH (KR) 2018-10-31 EP claimed
EP-2193136-B1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NAT RECH SCIENT (FR) 2014-07-30 EP claimed
EP-2193137-B1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NAT RECH SCIENT (FR) 2013-07-10 EP claimed
EP-2013262-B1 TWO STEP PREPARATION OF RANDOM POLYOXADIAZOLE COPOLYMER AND ARTICLES RESULTING THEREFROM DU PONT (US) 2012-02-01 EP claimed
EP-0856025-B1 CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE CELANESE VENTURES GMBH (DE) 2003-01-15 EP claimed
EP-0856025-B1 CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE CELANESE VENTURES GMBH (DE) 2003-01-15 EP disclosed
EP-0856025-A1 CHOLESTERIC PHASE-FORMING POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) 1998-08-05 EP disclosed
WO-1997014739-A1 CHOLESTERIC PHASE-FORMING POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE HOECHST RESEARCH & TECHNOLOGY (DE) 1997-04-24 WO disclosed
EP-0189073-B1 THERMOTROPIC AROMATIC POLYESTERS WITH HIGH HEAT STABILITY, PROCESS FOR THEIR FABRICATION AND THEIR USE FOR THE FABRICATION OF MOULDED ARTICLES, OF FILAMENTS, OF FIBRES AND FILMS BAYER AG (DE) 1990-08-01 EP disclosed
EP-0374657-A2 Thermotropic polyesters, process for their preparation and their use in the preparation of moulding compositions, filaments, fibres and films BAYER AG (DE) 1990-06-27 EP disclosed
EP-0221316-B1 THERMOTROPIC AROMATIC POLYESTER HAVING A HIGH DIMENSIONAL HEAT STABILITY AND EXCELLENT MECHANICAL PROPERTIES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF MOULDED ARTICLES, FILAMENTS, FABRICS AND SHEETS BAYER AG (DE) 1990-01-03 EP disclosed
EP-0275906-A2 Unsaturated polyester resins containing thermotropic polymers, process for their fabrication and their use for the fabrication of moulded articles BAYER AG (DE) 1988-07-27 EP disclosed
EP-0221316-A1 Thermotropic aromatic polyester having a high dimensional heat stability and excellent mechanical properties, process for their preparation and their use in the production of moulded articles, filaments, fabrics and sheets BAYER AG (DE) 1987-05-13 EP disclosed
EP-0205855-A1 Thermotropic aromatic polyesters having excellent mechanical properties and a good processability, process for preparing them and their use in the production of moulded articles, filaments, fibres and films BAYER AG (DE) 1986-12-30 EP disclosed
EP-0093333-B1 BLENDS OF MESOMORPHOUS CONDENSATION POLYMERS AND PARTLY CRYSTALLINE THERMOPLASTICS, PROCESS FOR THEIR PRODUCTION, AND THEIR USES IN THE PRODUCTION OF MOULDED ARTICLES BAYER AG (DE) 1986-09-03 EP disclosed
EP-0189073-A2 Thermotropic aromatic polyesters with high heat stability, process for their fabrication and their use for the fabrication of moulded articles, of filaments, of fibres and films BAYER AG (DE) 1986-07-30 EP disclosed
EP-0093333-A1 Blends of mesomorphous condensation polymers and partly crystalline thermoplastics, process for their production, and their uses in the production of moulded articles BAYER AG (DE) 1983-11-09 EP disclosed
EP-0088286-A1 Reinforced polyalkylene terephthalates, process for their preparation and their use in the production of moulded articles BAYER AG (DE) 1983-09-14 EP disclosed