Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 19/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985718 | 0.91 | AURKA (0.40) | AURKAADORA2AADORA2BADORA1 | |
| SCHEMBL212761 | 0.90 | AURKA (0.57) | AURKAADORA2AADORA2BADORA1 | |
| SCHEMBL4757462 | 0.87 | AURKA (0.60) | AURKA | |
| SCHEMBL209563 | 0.86 | AURKA (0.57) | AURKA | |
| SCHEMBL4756460 | 0.86 | AURKA (0.43) | AURKA | |
| SCHEMBL13985714 | 0.85 | AURKA (0.51) | AURKA | |
| SCHEMBL208764 | 0.85 | AURKA (0.51) | AURKA | |
| SCHEMBL13985671 | 0.85 | AURKA (0.48) | AURKA | |
| SCHEMBL13985716 | 0.85 | AURKA (0.62) | AURKA | |
| SCHEMBL13985472 | 0.83 | AURKA (0.42) | AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |