Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12775642 | 0.71 | MET (0.34) | MET | |
| SCHEMBL138622 | 0.58 | ADORA2A (0.36) | — | |
| SCHEMBL29357583 | 0.58 | ADORA2A (0.36) | — | |
| SCHEMBL13852954 | 0.55 | — | — | |
| SCHEMBL30736054 | 0.54 | — | — | |
| SCHEMBL16878060 | 0.53 | — | — | |
| SCHEMBL20698420 | 0.53 | ADORA2A (0.39) | — | |
| SCHEMBL20698663 | 0.50 | ADORA2A (0.38) | — | |
| SCHEMBL20698656 | 0.50 | ADORA2A (0.38) | — | |
| SCHEMBL18526535 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |