Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 18/20 | 0.51 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985647 | 0.88 | AURKA (0.51) | TBK1AURKA | |
| SCHEMBL211958 | 0.88 | AURKA (0.52) | TBK1AURKA | |
| SCHEMBL13985739 | 0.87 | TBK1 (0.52) | TBK1WNT3AIKBKE | |
| SCHEMBL13985706 | 0.87 | AURKA (0.44) | TBK1AURKA | |
| SCHEMBL13985592 | 0.86 | TBK1 (0.42) | TBK1AURKA | |
| SCHEMBL4757466 | 0.86 | AURKA (0.64) | AURKA | |
| SCHEMBL13985741 | 0.85 | AURKA (0.43) | TBK1WNT3AAURKA | |
| SCHEMBL4757493 | 0.85 | AURKA (0.54) | AURKA | |
| SCHEMBL211868 | 0.84 | AURKA (0.48) | TBK1WNT3AAURKA | |
| SCHEMBL210953 | 0.83 | AURKA (0.54) | TBK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |