Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.38 |
| ▸ | PTPRB | P23467 | 3/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.33 |
| ▸ | PTPRC | P08575 | 3/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705667 | 0.89 | PTPN1 (0.38) | PTPN1PTPN2PTPN6PTPRBPTPN11 | |
| SCHEMBL4688280 | 0.79 | SLC2A1 (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL4690935 | 0.78 | SLC2A1 (0.39) | PTPN1 | |
| SCHEMBL4706538 | 0.75 | TLR7 (0.39) | PTPN1 | |
| SCHEMBL4707566 | 0.75 | PTPN1 (0.42) | PTPN1PTPN2PTPN6PTPRBPTPN11 | |
| Trifluoroacetic Acid SCHEMBL4705925 | 0.75 | TLR7 (0.36) | PTPN1 | |
| SCHEMBL4691391 | 0.71 | SLC2A1 (0.36) | PTPN1 | |
| SCHEMBL4688933 | 0.70 | SLC2A1 (0.40) | PTPN1 | |
| SCHEMBL4710085 | 0.70 | GRIN2B (0.38) | PTPN1 | |
| SCHEMBL4706331 | 0.69 | CYP1A2 (0.39) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633754-B1 | DIAMINOPYRROLOQUINAZOLINES COMPOUNDS AS PROTEIN TYROSINE PHOSPHATASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-06-11 | — | — | EP | claimed |