Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327714 | 0.89 | BCHE (0.43) | BCHEACHEBACE1HRH4HRH3 | |
| SCHEMBL8321870 | 0.89 | S1PR5 (0.46) | BCHEACHEBACE1HRH4HRH3 | |
| SCHEMBL26252666 | 0.83 | BCHE (0.44) | BCHEACHEBACE1HRH4HRH3 | |
| SCHEMBL25389568 | 0.83 | BCHE (0.44) | BCHEACHEBACE1S1PR5DRD2 | |
| SCHEMBL26252672 | 0.83 | BCHE (0.44) | BCHEACHEBACE1HRH4HRH3 | |
| SCHEMBL22731735 | 0.82 | ALDH1A1 (0.53) | BCHEACHEBACE1HRH4HRH3 | |
| SCHEMBL8327594 | 0.80 | S1PR5 (0.47) | BCHEACHEBACE1HRH4HRH3 | |
| SCHEMBL2917086 | 0.80 | S1PR5 (0.54) | BCHEACHEBACE1HRH3S1PR5 | |
| SCHEMBL2922811 | 0.80 | S1PR5 (0.50) | S1PR5MAPT | |
| SCHEMBL22731741 | 0.79 | KDM4E (0.59) | BCHEACHEBACE1S1PR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| EP-3746421-B1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2023-11-29 | — | — | EP | disclosed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |