Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | PPARG | P37231 | 9/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756241 | 1.00 | PPARA (0.46) | PPARAPPARGNR1H4EPHX2SMN1; SMN2 | |
| SCHEMBL4757538 | 0.90 | NR1H4 (0.43) | PPARAPPARGNR1H4EPHX2SMN1; SMN2 | |
| SCHEMBL4757529 | 0.87 | PPARG (0.56) | PPARAPPARG | |
| SCHEMBL4758642 | 0.87 | PPARG (0.56) | PPARAPPARG | |
| SCHEMBL6714818 | 0.87 | PPARG (0.55) | PPARAPPARGPPARDLMNA | |
| SCHEMBL4789840 | 0.87 | PPARG (0.56) | PPARAPPARG | |
| SCHEMBL6716069 | 0.86 | PPARA (0.50) | PPARAPPARGPPARD | |
| SCHEMBL6716374 | 0.85 | PPARA (0.45) | PPARAPPARGNR1H4EPHX2NR4A2 | |
| SCHEMBL4757418 | 0.85 | PPARA (0.45) | PPARAPPARGNR1H4EPHX2NR4A2 | |
| SCHEMBL6713389 | 0.85 | L3MBTL1 (0.47) | PPARAPPARGSMN1; SMN2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |