Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3183513 | 0.79 | TSHR (0.68) | FAAHTDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL27540219 | 0.78 | TSHR (0.66) | FAAHTDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL3099269 | 0.77 | FAAH (0.43) | FAAHTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL22474206 | 0.76 | TDP1 (0.58) | FAAHTDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL27579434 | 0.76 | TDP1 (0.58) | FAAHTDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL5324746 | 0.75 | FAAH (0.40) | FAAHTDP1KMT2AKEAP1MEN1 | |
| SCHEMBL24437485 | 0.75 | TDP1 (0.51) | FAAHTDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL9136464 | 0.75 | TDP1 (0.51) | FAAHTDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL13335586 | 0.74 | TDP1 (0.54) | FAAHTDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL29699649 | 0.73 | TDP1 (0.58) | FAAHTDP1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013860-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008013860-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-01-31 | — | — | WO | disclosed |