Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 9/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13014338 | 0.89 | SLC2A1 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL4759561 | 0.87 | SLC2A1 (0.46) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL3775156 | 0.84 | KCNH2 (0.79) | KCNH2SLC2A1 | |
| SCHEMBL4760076 | 0.84 | KCNH2 (0.57) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL3769272 | 0.83 | SLC2A1 (0.53) | KCNH2SLC2A1 | |
| SCHEMBL3786610 | 0.81 | KCNH2 (0.74) | KCNH2SLC2A1 | |
| SCHEMBL3779600 | 0.81 | KCNH2 (0.63) | KCNH2SLC2A1 | |
| SCHEMBL3775094 | 0.81 | KCNH2 (0.53) | KCNH2SLC2A1 | |
| SCHEMBL14519825 | 0.79 | SLC2A1 (0.76) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL3780005 | 0.78 | KCNH2 (0.56) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943222-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042325-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2007-04-19 | — | — | WO | disclosed |