Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 8/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13014300 | 0.90 | SLC2A1 (0.55) | SLC2A1KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL4758370 | 0.87 | KCNH2 (0.58) | SLC2A1KCNH2MCHR1 | |
| SCHEMBL6111878 | 0.86 | KCNH2 (0.59) | SLC2A1KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL3774520 | 0.86 | KCNH2 (0.59) | SLC2A1KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL13014321 | 0.85 | TSHR (0.46) | SLC2A1KCNH2HTR1AMCHR1HTR1D | |
| SCHEMBL3777163 | 0.83 | HTR1A (0.42) | KCNH2HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL3782147 | 0.82 | KCNH2 (0.59) | SLC2A1KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL3779625 | 0.81 | HTR1A (0.55) | KCNH2HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL3802794 | 0.80 | KCNH2 (0.62) | SLC2A1KCNH2 | |
| SCHEMBL3781197 | 0.79 | KCNH2 (0.47) | SLC2A1KCNH2HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943222-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042325-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2007-04-19 | — | — | WO | disclosed |