Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758901 | 0.83 | TYMS (0.33) | HTR3A | |
| SCHEMBL4758909 | 0.73 | KDM4E (0.37) | — | |
| SCHEMBL4757942 | 0.72 | ADORA1 (0.34) | — | |
| SCHEMBL1337886 | 0.68 | PNP (0.42) | — | |
| SCHEMBL4756129 | 0.65 | — | — | |
| SCHEMBL28004985 | 0.65 | PNP (0.40) | — | |
| SCHEMBL27523662 | 0.65 | PNP (0.40) | — | |
| SCHEMBL28004484 | 0.65 | PNP (0.40) | — | |
| SCHEMBL28248838 | 0.61 | MCHR1 (0.43) | HTR3A | |
| SCHEMBL27491043 | 0.60 | PNP (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1897882-B1 | N2-QUINOLYL OR ISOQUINOLYL SUBSTITUTED PURINE DERIVATIVES, THE PREPARATION AND USES THEREOF | ZHE JIANG MEDECINE CO LTD XINCHANG PHARMACEUTICAL FACTORY (CN) | 2014-12-10 | — | — | EP | disclosed |
| EP-1897882-A1 | N2-QUINOLYL OR ISOQUINOLYL SUBSTITUTED PURINE DERIVATIVES, THE PREPARATION AND USES THEREOF | Zhe Jiang Medecine Co., Ltd. Xinchang Pharmaceutical Factory (CN) | 2008-03-12 | — | — | EP | disclosed |