SCHEMBL4758678

SCHEMBL4758678

CCCCCCCCCCCCCCCC/C=C/P(=O)(OC)OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.49
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
PLA2G4A P47712 1/20 0.49
PAFAH1B2 P68402 1/20 0.49
KMT2A Q03164 1/20 0.49
MGLL Q99685 1/20 0.49
ABHD6 Q9BV23 1/20 0.49
TRPV1 Q8NER1 1/20 0.47
LPAR3 Q9UBY5 2/20 0.46
LPAR1 Q92633 1/20 0.44
LPAR2 Q9HBW0 1/20 0.44
GGPS1 O95749 1/20 0.42
TSHR P16473 1/20 0.41
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2570293 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL4758679 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL2573447 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL8051911 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL2576632 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL2567546 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL2567548 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL2573446 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL8051913 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A
SCHEMBL2570295 1.00 FAAH (0.49) FAAHMAPTMEN1ALDH1A1PLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060264340-A1 Fluid compositions for dual clutch transmissions AFTON CHEMICAL CORPORATION 2006-11-23 US claimed
US-20080280791-A1 Lubricating Oil Composition for Marine Applications AFTON CHEMICAL CORPORATION 2008-11-13 US disclosed
EP-1990400-A2 Lubricating oil composition for marine applications Afton Chemical Corporation (US) 2008-11-12 EP disclosed
US-20060264340-A1 Fluid compositions for dual clutch transmissions AFTON CHEMICAL CORPORATION 2006-11-23 US disclosed
EP-0042270-B1 LUBRICATING OIL ADDITIVE, METHOD FOR MAKING THE SAME, LUBRICATING OIL ADDITIVE PACKAGE, AND LUBRICATING OIL COMPOSITION COMPRISING THE SAME, AND THE USE OF CERTAIN SUCCINIMIDES IN FORMING OIL ADDITIVES EDWIN COOPER INC. (US) 1984-09-12 EP disclosed
US-4331545-A FRICTION RESISTANCE IN INTERNAL COMBUSTION ENGINES EDWIN COOPER, INC. (US) 1982-05-25 US disclosed
US-4325827-A FRICTION RESISTANCE EDWIN COOPER, INC. (US) 1982-04-20 US disclosed
EP-0042270-A2 Lubricating oil additive, method for making the same, lubricating oil additive package, and lubricating oil composition comprising the same, and the use of certain succinimides in forming oil additives EDWIN COOPER INC. (US) 1981-12-23 EP disclosed
US-4295983-A Lubricating oil composition containing boronated N-hydroxymethyl succinimide friction reducers ETHYL CORPORATION (US) 1981-10-20 US disclosed
US-4293432-A N-/2-HYDROXYETHYL/FATTY ACID AMIDE, FRICTION RESISTANCE ETHYL CORPORATION (US) 1981-10-06 US disclosed
US-4246125-A ALIPHATIC HYDROCARBYL SULFINYL OR SULFONYL METHANE EDWIN COOPER, INC. (US) 1981-01-20 US disclosed
US-4237020-A N-ALIPHATIC HYDROCARBYL HYDROXYALKYLSULFINYLSUCCINIMIDE OR N-ALIPHATIC HYDROCARBYL HYDROXYALKYLSULFONYLSUCCINIMIDE EDWIN COOPER, INC. (US) 1980-12-02 US disclosed
US-4225449-A HYDROCARBYLSULFONYL OR SULFINYL ALKANOL EDWIN COOPER, INC. (US) 1980-09-30 US disclosed
US-4158633-A DIMETHYLHYDROCARBYLPHOSPHONATE OIL ADDITIVE TO LOWER FUEL CONSUMPTION EDWIN COOPER, INC. (US) 1979-06-19 US disclosed