SCHEMBL475888

SCHEMBL475888

CC(C)(CCCCN)c1ccccc1C(C)(C)CCCCN

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 10/20 0.42
TAAR1 Q96RJ0 1/20 0.40
MAOA P21397 1/20 0.40
KCNH2 Q12809 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HRH1 P35367 2/20 0.34
HTR2A P28223 1/20 0.34
CXCR4 P61073 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL858707 0.81 TAAR1 (0.59) KIF11TAAR1MAOAKCNH2CYP3A4
SCHEMBL11216774 0.80 CNR2 (0.43) CNR1CNR2
SCHEMBL11445241 0.78 CNR2 (0.46) CNR1CNR2
SCHEMBL475887 0.77 CNR2 (0.44) KIF11TAAR1KCNH2CNR1CNR2
SCHEMBL7776255 0.77 CNR2 (0.43) CNR1CNR2
SCHEMBL7370382 0.76 HTR2A (0.45) TAAR1CYP3A4CYP2D6CYP2C19HTR2A
SCHEMBL10978703 0.74 TAAR1 (0.61) TAAR1CYP3A4CYP2D6HTR2A
Hydrochloric Acid SCHEMBL7976097 0.74 CNR2 (0.43) CNR1CNR2
SCHEMBL10961754 0.72 KIF11 (0.55) KIF11TAAR1MAOAKCNH2CYP3A4
SCHEMBL22623947 0.72 TAAR1 (0.39) KIF11TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240343879-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2024-10-17 US claimed
US-12054598-B2 Polymer aerogel with improved mechanical and thermal properties Blueshift Materials, Inc. (US) 2024-08-06 US claimed
US-20220380568-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2022-12-01 US claimed
US-11427693-B2 Polymer aerogel with improved mechanical and thermal properties BLUESHFT MATERIALS, INC. (US) 2022-08-30 US claimed
EP-3368198-B1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT MAT INC (US) 2022-07-06 EP claimed
US-20200277464-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2020-09-03 US claimed
US-10626239-B2 Polymer aerogel with improved mechanical and thermal properties Blueshift Materials, Inc. (US) 2020-04-21 US claimed
US-20180305514-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2018-10-25 US claimed
CN-105392822-B Aeroge synthetic method 耐克索尔夫公司 2018-08-14 CN claimed
US-9963571-B2 Polymer aerogel with improved mechanical and thermal properties Blueshift Materials, Inc. (US) 2018-05-08 US claimed
US-20150025192-A1 Black Polyimides and Synthesis Thereof NEXOLVE CORPORATION (US) 2015-01-22 US claimed
US-20140350134-A1 Method of Aerogel Synthesis BARINGS FINANCE LLC, AS COLLATERAL AGENT 2014-11-27 US claimed
US-20120190802-A1 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATION (US) 2012-07-26 US claimed
US-7785517-B2 Methods for reducing or eliminating defects in polymer workpieces NEXOLVE CORPORATION (US) 2010-08-31 US claimed
US-20090054615-A1 Methods For Reducing Or Eliminating Defects In Polymer Workpieces BARINGS FINANCE LLC, AS COLLATERAL AGENT 2009-02-26 US claimed
EP-1395627-B1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH DU PONT (US) 2006-11-02 EP claimed
EP-1395627-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-10 EP claimed
US-6653433-B2 From polyamic acids E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-25 US claimed
WO-2002090422-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-11-14 WO claimed
US-20020010311-A1 From polyamic acids E.I. DU PONT DE NEMOURS AND COMPANY 2002-01-24 US claimed