Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317224 | 0.82 | TSHR (0.34) | TSHR | |
| SCHEMBL317223 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL1744844 | 0.67 | TSHR (0.34) | TSHR | |
| SCHEMBL7360415 | 0.64 | TSHR (0.35) | TSHR | |
| SCHEMBL8248277 | 0.61 | TSHR (0.37) | TSHR | |
| SCHEMBL7364139 | 0.60 | TSHR (0.32) | TSHR | |
| SCHEMBL11325482 | 0.57 | TSHR (0.41) | TSHR | |
| SCHEMBL667047 | 0.56 | TSHR (0.57) | TSHR | |
| SCHEMBL11956562 | 0.56 | TSHR (0.39) | TSHR | |
| SCHEMBL11956563 | 0.56 | TSHR (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973886-A2 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | Janssen Pharmaceutica, N.V. (BE) | 2008-10-01 | — | — | EP | claimed |
| WO-2007079163-A2 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-12 | — | — | WO | claimed |