SCHEMBL475934

SCHEMBL475934

CCOC(=O)/C=C/C(=O)O[Si](CC)(CC)CC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.57
MAPT P10636 8/20 0.43
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
LMNA P02545 5/20 0.40
HTT P42858 1/20 0.40
ALOX15 P16050 1/20 0.39
MDM2 Q00987 2/20 0.39
ALDH1A1 P00352 3/20 0.39
THRB P10828 1/20 0.39
TTR P02766 1/20 0.38
DPP4 P27487 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
MDM4 O15151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476044 1.00 HCAR2 (0.57) HCAR2MAPTATMNPSR1CA12
SCHEMBL475937 1.00 HCAR2 (0.57) HCAR2MAPTATMNPSR1CA12
SCHEMBL28370169 0.89 HCAR2 (0.39) HCAR2MAPTATMNPSR1ALOX15
SCHEMBL4646701 0.85 HCAR2 (0.50) HCAR2MAPTATMNPSR1CA12
SCHEMBL4643577 0.85 HCAR2 (0.50) HCAR2MAPTATMNPSR1CA12
SCHEMBL4643586 0.85 HCAR2 (0.50) HCAR2MAPTATMNPSR1CA12
SCHEMBL4642111 0.82 HCAR2 (0.47) HCAR2MAPTATMNPSR1CA12
SCHEMBL4642097 0.82 HCAR2 (0.47) HCAR2MAPTATMNPSR1CA12
SCHEMBL4642397 0.82 HCAR2 (0.47) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL42602 0.82 HCAR2 (0.80) HCAR2MAPTATMNPSR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912120-B1 ANTIFOULING COATING COMPOSITION JOTUN AS (NO) 2017-12-20 EP disclosed
CN-103658097-B Cleaning method 佐敦集团 2017-03-01 CN disclosed
EP-2725073-B1 Antifouling coating composition JOTUN AS (NO) 2016-08-03 EP disclosed
EP-2912120-A1 ANTIFOULING COATING COMPOSITION Jotun A/S (NO) 2015-09-02 EP disclosed
WO-2014064048-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
WO-2014064049-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
EP-2725073-A1 Antifouling coating composition Jotun A/S (NO) 2014-04-30 EP disclosed
CN-103658097-A Cleaning process JOTUN AS 2014-03-26 CN disclosed
EP-2708594-A1 Cleaning process Jotun A/S (NO) 2014-03-19 EP disclosed
CN-102083925-B Binder for antifouling coating composition and antifouling coating composition comprising binder JOTUN AS 2013-11-06 CN disclosed
WO-2009149919-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2009-12-17 WO disclosed
WO-2009007276-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2009-01-15 WO disclosed
EP-1476509-B1 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2007-04-11 EP disclosed
EP-1476509-A2 SELF-POLISHING ANTIFOULING PAINT Jotun AS (NO) 2004-11-17 EP disclosed
WO-2003070832-A2 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2003-08-28 WO disclosed
CN-1086406-C Coating composition NIPPON OILS & FATS BASF COATIN (JP) 2002-06-19 CN disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
CN-1167797-A Coating composition NOF CORP (JP) 1997-12-17 CN disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed