SCHEMBL4642111

SCHEMBL4642111

CCOC(=O)C=CC(=O)OCCC(=O)O[Si](CC)(CC)CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.47
ATM Q13315 1/20 0.43
MAPT P10636 7/20 0.37
NPSR1 Q6W5P4 2/20 0.37
RAB9A P51151 1/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 1/20 0.35
MDM2 Q00987 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TTR P02766 1/20 0.33
DPP4 P27487 1/20 0.33
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642097 1.00 HCAR2 (0.47) HCAR2ATMMAPTNPSR1RAB9A
SCHEMBL4642397 1.00 HCAR2 (0.47) HCAR2ATMMAPTNPSR1RAB9A
SCHEMBL4642329 0.90 ATM (0.49) HCAR2ATMMAPTNPSR1RAB9A
SCHEMBL4642341 0.90 ATM (0.49) HCAR2ATMMAPTNPSR1RAB9A
SCHEMBL4645104 0.90 ATM (0.49) HCAR2ATMMAPTNPSR1RAB9A
SCHEMBL4645298 0.89 ATM (0.47) HCAR2ATMMAPTNPSR1RAB9A
SCHEMBL4641658 0.89 ATM (0.47) HCAR2ATMMAPTNPSR1RAB9A
SCHEMBL4641670 0.89 ATM (0.47) HCAR2ATMMAPTNPSR1RAB9A
SCHEMBL4643586 0.83 HCAR2 (0.50) HCAR2ATMMAPTNPSR1CA12
SCHEMBL4646701 0.83 HCAR2 (0.50) HCAR2ATMMAPTNPSR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed