SCHEMBL475973

SCHEMBL475973

O=C(O)c1ccc(C(=O)O)c(C(=O)Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.60
CDC25A P30304 1/20 0.52
CDC25B P30305 1/20 0.52
HSD17B10 Q99714 1/20 0.52
POLB P06746 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TSHR P16473 4/20 0.48
TP53 P04637 1/20 0.46
MYC P01106 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
PTGS2 P35354 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6560811 0.93 KDM4E (0.52) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL8306753 0.91 CDC25B (0.52) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL11701892 0.91 KDM4E (0.55) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL30163040 0.86 KDM4E (0.69) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL23861 0.86 KDM4E (0.69) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL29899307 0.86 KDM4E (0.69) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL29350135 0.86 KDM4E (0.69) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL23279 0.86 KDM4E (0.69) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL4613753 0.84 HSD17B10 (0.59) KDM4ECDC25ACDC25BHSD17B10POLB
SCHEMBL8180385 0.84 KDM4E (0.67) KDM4ECDC25ACDC25BHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1069 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117000047-B Oxidation-resistant, antibacterial and high-flux reverse osmosis membrane and preparation method and application thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-120054221-A High-temperature-resistant composite reverse osmosis membrane and preparation method thereof 沃顿科技股份有限公司 2025-05-30 CN claimed
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-119971778-A Preparation method and application of nanoparticle blending modified forward osmosis membrane 宁波大学 2025-05-13 CN claimed
CN-116510764-B Preparation method of micro-filtration/nanofiltration double-layer catalytic membrane based on double-site carbon nitride and in-situ self-Fenton application thereof 苏州科技大学 2025-02-28 CN claimed
CN-119327283-A Composite reverse osmosis membrane and preparation method thereof 万华化学集团股份有限公司 2025-01-21 CN claimed
CN-119075715-A Composite nanofiltration membrane, preparation method and application thereof 北京宝盛通国际电气工程技术有限公司 2024-12-06 CN claimed
CN-118922494-A Transparent polycarbonate compositions 高新特殊工程塑料全球技术有限公司 2024-11-08 CN claimed
CN-118849554-A Preparation method of PA film with PVDF dendritic fiber film as supporting layer 安徽工程大学 2024-10-29 CN claimed
EP-0072002-B1 HIGH PERFORMANCE SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PRODUCING SAME TORAY INDUSTRIES, INC. (JP) 1985-04-10 EP claimed
US-4452966-A REACTING A POLYCARBONATE OLIGOMER WITH A THREE FUNCTIONAL GROUP COMPOUND, THEN A DIHYDRIC PHENOL IDEMITSU KOSAN COMPANY LIMITED (JP) 1984-06-05 US claimed
EP-0093914-A1 Process for the production of polycarbonate IDEMITSU KOSAN COMPANY LIMITED (JP) 1983-11-16 EP claimed
EP-0072002-A1 High performance semipermeable composite membrane and process for producing same TORAY INDUSTRIES, INC. (JP) 1983-02-16 EP claimed
EP-0067693-A1 Acid halide and acyllactam functional materials DSM RIM NYLON V.O.F (NL) 1982-12-22 EP claimed
EP-0067695-A1 Process for the preparaton of nylon block polymers DSM RIM NYLON V.O.F (NL) 1982-12-22 EP claimed
EP-0041551-A4 BLENDS OF POLYETHERIMIDES AND POLYAMIDEIMIDES. GEN ELECTRIC (US) 1982-04-22 EP claimed
EP-0041551-A1 BLENDS OF POLYETHERIMIDES AND POLYAMIDEIMIDES. GEN ELECTRIC (US) 1981-12-16 EP claimed
WO-1981001568-A1 BLENDS OF POLYETHERIMIDES AND POLYAMIDEIMIDES GEN ELECTRIC (US) 1981-06-11 WO claimed
US-4258155-A FOR COATINGS AND MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1981-03-24 US claimed