SCHEMBL6560811

SCHEMBL6560811

O=C(O)c1ccc(C(=O)Cl)c(C(=O)Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
TSHR P16473 3/20 0.50
TP53 P04637 1/20 0.48
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA4 P22748 3/20 0.46
CA6 P23280 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA14 Q9ULX7 3/20 0.46
POLB P06746 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 2/20 0.46
GAA P10253 1/20 0.46
PTGS2 P35354 1/20 0.46
ALOX15 P16050 1/20 0.44
CDC25A P30304 1/20 0.44
CDC25B P30305 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11701892 0.93 KDM4E (0.55) KDM4ETSHRTP53CA12CA1
SCHEMBL475973 0.93 KDM4E (0.60) KDM4ETSHRTP53CA12CA1
SCHEMBL29440655 0.86 ALDH1A1 (0.40) KDM4ETSHRTP53CA1CA2
SCHEMBL75886 0.86 ALDH1A1 (0.40) KDM4ETSHRTP53CA1CA2
SCHEMBL11704191 0.84 HSD17B10 (0.52) KDM4ETSHRTP53CA12CA1
SCHEMBL8306753 0.84 CDC25B (0.52) KDM4ETSHRTP53CA12CA1
SCHEMBL338194 0.84 TDP1 (0.48) KDM4ETSHRPOLBL3MBTL1MAPT
SCHEMBL11707257 0.83 CA12 (0.59) KDM4ETSHRTP53CA12CA1
SCHEMBL5383734 0.83 TSHR (0.50) KDM4ETSHRTP53CA12CA1
SCHEMBL11701793 0.83 CA1 (0.59) KDM4ETSHRTP53CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112973473-A Reverse osmosis composite membrane resisting biological pollution and preparation method thereof 天津工业大学 2021-06-18 CN claimed
CN-119775242-B Method for synthesizing 5-cyanophthalide 内蒙古源宏精细化工有限公司 2025-08-15 CN disclosed
CN-119775242-A Method for synthesizing 5-cyanophthalide 内蒙古源宏精细化工有限公司 2025-04-08 CN disclosed
CN-112973473-A Reverse osmosis composite membrane resisting biological pollution and preparation method thereof 天津工业大学 2021-06-18 CN disclosed
US-20210121499-A1 THERAPEUTIC AGENT FOR HYPERPHOSPHATEMIA AND PARTICLES FUJIFILM CORPORATION (JP) 2021-04-29 US disclosed
EP-3698798-A1 HYPERPHOSPHATEMIA TREATMENT AGENT, AND PARTICLES FUJIFILM Corporation (JP) 2020-08-26 EP disclosed
US-20190321393-A1 THERAPEUTIC AGENT FOR HYPERPHOSPHATEMIA AND PARTICLES FUJIFILM CORPORATION (JP) 2019-10-24 US disclosed
US-20150361257-A1 METHOD FOR PRODUCING SUBSTRATE HAVING PATTERN AND RESIN COMPOSITION FOR HYDROFLUORIC ACID ETCHING NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-17 US disclosed
EP-0735403-B1 Liquid crystal orienting agent JSR CORP (JP) 2004-03-17 EP disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed
EP-0735403-A1 Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed
US-4618633-A Halogen-free self-extinguishing thermoplastic molding material BASF AKTIENGESELLSCHAFT (DE) 1986-10-21 US disclosed
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed
US-3984375-A Aromatic amide-imide polymers WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210121499-A1 THERAPEUTIC AGENT FOR HYPERPHOSPHATEMIA AND PARTICLES PTH1R, SLC34A1, SLC20A1 KDM4E 4561/4885TSHR 249/4885TP53 2048/4885
US-20190321393-A1 THERAPEUTIC AGENT FOR HYPERPHOSPHATEMIA AND PARTICLES PTH1R, SLC34A1, SLC20A1 KDM4E 4561/4885TSHR 249/4885TP53 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.