Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872704 | 0.88 | GRM5 (0.68) | GRM5SLC6A2 | |
| Hydrochloric Acid SCHEMBL3874011 | 0.87 | GRM5 (0.67) | GRM5SLC6A2 | |
| SCHEMBL3871676 | 0.87 | GRM5 (0.70) | GRM5SLC6A2 | |
| Hydrochloric Acid SCHEMBL3876458 | 0.86 | GRM5 (0.68) | GRM5SLC6A2 | |
| SCHEMBL3877004 | 0.82 | GRM5 (1.00) | GRM5SLC6A2 | |
| SCHEMBL1477622 | 0.82 | CHRNB2 (0.48) | GRM5 | |
| Hydrochloric Acid SCHEMBL4654166 | 0.81 | GRM5 (0.97) | GRM5SLC6A2 | |
| SCHEMBL3873559 | 0.75 | GRM5 (0.76) | GRM5SLC6A2 | |
| Hydrochloric Acid SCHEMBL3876196 | 0.74 | GRM5 (0.74) | GRM5SLC6A2 | |
| SCHEMBL1476588 | 0.73 | CHRNB2 (0.54) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603877-B1 | NOVEL AMINOPYRIDINE DERIVATIVES AS mGIuR5 ANTAGONISTS | ADDEX PHARMA SA (CH) | 2008-11-26 | — | — | EP | claimed |