SCHEMBL4759931

SCHEMBL4759931

Nc1ccc2c(c1)oc(=O)c1cc(N)ccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
KMT2A Q03164 4/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
MAPK1 P28482 2/20 0.62
PDE2A O00408 1/20 0.56
PKM P14618 2/20 0.54
ALPL P05186 1/20 0.54
ALPI P09923 1/20 0.54
KDM4E B2RXH2 7/20 0.53
ALDH1A1 P00352 7/20 0.53
MAPT P10636 6/20 0.53
HPGD P15428 4/20 0.53
MEN1 O00255 3/20 0.53
GAA P10253 2/20 0.53
CASP1 P29466 2/20 0.53
CASP7 P55210 2/20 0.53
HSD17B10 Q99714 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8236490 0.89 KMT2A (0.74) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL26778888 0.88 KMT2A (0.50) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL27323033 0.88 PDE2A (0.77) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL1315246 0.88 PDE2A (0.77) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL30629174 0.88 PDE2A (0.77) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL26767941 0.88 KDM4E (0.54) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL2392285 0.87 RAB9A (0.77) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL30629159 0.84 KDM4E (0.79) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL26778956 0.84 KMT2A (0.46) NPC1RAB9AKMT2ASMN1; SMN2MAPK1
SCHEMBL26768804 0.84 KDM4E (0.79) NPC1RAB9AKMT2ASMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008060128-A LAMINATE FOR WIRING BOARD NIPPON STEEL CHEM CO LTD 2008-03-13 JP disclosed
JP-2007197583-A AROMATIC POLYAMIC ACID AND AROMATIC POLYIMIDE NIPPON STEEL CHEM CO LTD 2007-08-09 JP disclosed
WO-2007086550-A1 LAMINATE FOR WIRING BOARD NIPPON STEEL CHEMICAL CO., LTD. (JP) 2007-08-02 WO disclosed
JP-2007131575-A METHOD OF MANUFACTURING 3,8-DIAMINODIBENZOPYRANONE NIPPON STEEL CHEM CO LTD 2007-05-31 JP disclosed