Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | PRNP | P04156 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007774 | 0.83 | AURKB (0.72) | ALDH1A1NPSR1HTTPTGS2ATM | |
| SCHEMBL8363505 | 0.81 | ATM (0.68) | ALDH1A1NPSR1HTTATMMAPT | |
| SCHEMBL11008262 | 0.78 | MAPT (0.64) | ALDH1A1NPSR1HTTATMMAPT | |
| SCHEMBL11010130 | 0.78 | AURKB (0.61) | ALDH1A1NPSR1HTTPTGS2ATM | |
| SCHEMBL4967076 | 0.75 | ATM (0.64) | ALDH1A1NPSR1HTTATMMAPT | |
| SCHEMBL4476411 | 0.75 | ALDH1A1 (0.71) | ALDH1A1NPSR1ATMMAPTMEN1 | |
| SCHEMBL11006526 | 0.74 | MAPT (0.59) | ALDH1A1NPSR1HTTATMMAPT | |
| Hydrochloric Acid SCHEMBL3519020 | 0.73 | ALDH1A1 (0.69) | ALDH1A1NPSR1ATMMAPTMEN1 | |
| SCHEMBL19046887 | 0.73 | SLC22A12 (0.71) | ALDH1A1NPSR1HTTATMMAPT | |
| SCHEMBL17153801 | 0.73 | ATM (0.78) | ALDH1A1NPSR1HTTATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-27 | — | — | US | disclosed |
| US-20080280963-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-13 | — | — | US | disclosed |
| EP-1931627-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007034251-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | ALDH1A1 1778/4885NPSR1 222/4885HTT 4829/4885 |
| US-20080280963-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | ALDH1A1 1778/4885NPSR1 222/4885HTT 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.