Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.51 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.51 |
| ▸ | BCAT2 | O15382 | 3/20 | 0.50 |
| ▸ | BTK | Q06187 | 3/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16179428 | 0.85 | IDO1 (0.49) | IDO1CSNK1A1DYRK1BTYRO3BCAT2 | |
| SCHEMBL7840196 | 0.84 | IDO1 (0.59) | IDO1BCAT2SCN4AKDM4EALDH1A1 | |
| SCHEMBL6527107 | 0.84 | BTK (0.48) | IDO1CSNK1A1DYRK1BTYRO3BCAT2 | |
| SCHEMBL681068 | 0.80 | LTA4H (0.47) | IDO1CSNK1A1DYRK1BTYRO3BCAT2 | |
| SCHEMBL29574471 | 0.80 | TDP1 (0.45) | IDO1BTKKDM4EALDH1A1MAPT | |
| SCHEMBL11767517 | 0.79 | IDO1 (0.53) | IDO1BCAT2CSF1RKDRFLT3 | |
| SCHEMBL25431026 | 0.77 | IDO1 (0.50) | IDO1BCAT2BTKSCN4ACD74 | |
| SCHEMBL31130647 | 0.77 | HCRTR1 (0.46) | IDO1CSNK1A1DYRK1BTYRO3BTK | |
| SCHEMBL30482307 | 0.77 | IDO1 (0.50) | IDO1BCAT2BTKSCN4ACD74 | |
| Hydrochloric Acid SCHEMBL29535738 | 0.76 | HCRTR1 (0.46) | CSNK1A1DYRK1BTYRO3BTKPLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106608873-B | Pyrazol acid amide compounds and the preparation method and application thereof | 湖南化工研究院有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-106608873-A | Pyrazole amide compound, and preparation method and application thereof | 湖南化工研究院有限公司 | 2017-05-03 | — | — | CN | claimed |
| EP-1928879-A2 | FUSED HETEROCYCLIC COMPOUNDS USEFUL AS KINASE MODULATORS | Brystol-Myers Squibb Company (US) | 2008-06-11 | — | — | EP | claimed |
| WO-2007038314-A2 | FUSED HETEROCYCLIC COMPOUNDS USEFUL AS KINASE MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-05 | — | — | WO | claimed |
| CN-119019387-A | 3-Substituted-1-H-indole pyrazole derivative compound, and preparation method and application thereof | 贵州大学 | 2024-11-26 | — | — | CN | disclosed |
| EP-4402137-A1 | PHENYL CORE COMPOUNDS AS MGLU5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME | Vanderbilt University (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-118271285-A | Azetidine-containing amide derivative, preparation method and application thereof | 贵州大学 | 2024-07-02 | — | — | CN | disclosed |
| WO-2023205680-A1 | PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023043823-A1 | PHENYL CORE COMPOUNDS AS MGLU5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME | VANDERBILT UNIVERSITY (US) | 2023-03-23 | — | — | WO | disclosed |
| WO-2020198053-A1 | 2-OXO-2,3-DIHYDRO-1H-IMIDAZO[4,5-B]PYRIDIN-6-YL)-4-METHYLBENZAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS RIPK2 INHIBITORS FOR TREATING E.G. AUTOIMMUNE DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-10-01 | — | — | WO | disclosed |
| CN-106608873-B | Pyrazol acid amide compounds and the preparation method and application thereof | 湖南化工研究院有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-106608872-B | 5- pyrazol acid amide compounds and the preparation method and application thereof | 湖南化工研究院有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-1517349-A | Two new compounds for treating impotence | 刘宝顺 | 2004-08-04 | — | — | CN | disclosed |
| CN-1495169-A | Pyridine-3-carboxylic acid derivative | — | 2004-05-12 | — | — | CN | disclosed |
| CN-1134442-C | Pyrazolopyrimidinone cGMP PDE5 inhibitor, preparation method and application thereof and intermediate | �������۸��¼��������������ι�˾ | 2004-01-14 | — | — | CN | disclosed |
| CN-1127506-C | Compound for treating impotence | LIU BAOSHUN (CN) | 2003-11-12 | — | — | CN | disclosed |
| EP-1282418-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | Serono Reproductive Biology Institute, Inc. (US) | 2003-02-12 | — | — | EP | disclosed |
| CN-1393444-A | Compound for treating impotence | LIU BAOSHUN (CN) | 2003-01-29 | — | — | CN | disclosed |
| WO-2001087287-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-11-22 | — | — | WO | disclosed |
| CN-1305478-A | Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction | PFIZER (US) | 2001-07-25 | — | — | CN | disclosed |