Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24122074 | 0.81 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL4014856 | 0.79 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL4019286 | 0.77 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL16370085 | 0.73 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL25344551 | 0.72 | NPC1 (0.33) | DGAT1 | |
| SCHEMBL29900915 | 0.71 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL27215111 | 0.71 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL19250755 | 0.71 | NPC1 (0.32) | DGAT1 | |
| SCHEMBL1593371 | 0.71 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL17837426 | 0.71 | NPC1 (0.38) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919470-A1 | FUSED PYRAZOLE AS p38 MAP KINASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007023105-A1 | FUSED PYRAZOLE AS p38 MAP KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-01 | — | — | WO | disclosed |