SCHEMBL476050

SCHEMBL476050

CCCCCCCC[Si](CCCCCCCC)CCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
THRB P10828 1/20 0.57
DNM1 Q05193 7/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC22A1 O15245 1/20 0.42
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475822 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1480045 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1033085 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL419899 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090776 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1556049 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090842 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090791 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090785 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090803 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 699 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3784677-A1 NON-COORDINATING ANION TYPE ACTIVATORS CONTAINING CATION HAVING LARGE ALKYL GROUPS ExxonMobil Chemical Patents Inc. (US) 2021-03-03 EP claimed
CN-112351987-A Non-coordinating anionic activators containing cations with large alkyl groups 埃克森美孚化学专利公司 2021-02-09 CN claimed
US-20190330139-A1 Non-Coordinating Anion Type Activators Containing Cation Having Large Alkyl Groups EXXONMOBIL CHEMICAL PATENTS INC. 2019-10-31 US claimed
US-7736634-B2 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2010-06-15 US claimed
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
US-20070235726-A1 Poly[bis(ethynyl)heteroacene]s and electronic devices generated therefrom XEROX CORPORATION 2007-10-11 US claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-1380611-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SigmaKalon Group B.V. (NL) 2004-01-14 EP claimed
EP-1208167-B1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES HEMPELS SKIBSFARVE FAB J C (DK) 2003-07-30 EP claimed
EP-1208167-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2002-05-29 EP claimed
WO-2000077102-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2000-12-21 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
CN-119081643-A Low-viscosity high-heat-conductivity organic silicon bonding pouring sealant and preparation method thereof 硅宝正基(深圳)科技有限公司 2024-12-06 CN disclosed
US-12041937-B2 Copper chelate complex compositions for antifouling protection ARXADA AG (CH) 2024-07-23 US disclosed
US-4892962-A FROM ALLYL DIFLUOROACETATES AND A MONOCHLORO=SILANE, ADDITION POLYMERS CIBA-GEIGY CORPORATION (US) 1990-01-09 US disclosed
US-4692536-A Process for the preparation of hemiaminals, and the use thereof CIBA-GEIGY CORPORATION (US) 1987-09-08 US disclosed
US-4015061-A Protected amino-functional initiators and amino-terminated polymers and their production THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof C1R, C9, PCBP1 TSHR 3690/4885THRB 4122/4885DNM1 3445/4885
US-20190330139-A1 Non-Coordinating Anion Type Activators Containing Cation Having Large Alkyl Groups KCNK10, KCNK4, HCN4 TSHR 3717/4885THRB 3969/4885DNM1 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.