Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 16/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA9 | Q16790 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012357 | 0.98 | KMT2A (0.50) | KMT2ACA2CA12CA1CA9 | |
| SCHEMBL4789468 | 0.85 | CA2 (0.46) | KMT2ACA2CA12CA1CA9 | |
| SCHEMBL2606680 | 0.76 | KMT2A (0.52) | KMT2APOLB | |
| SCHEMBL2120202 | 0.74 | KMT2A (0.50) | KMT2APOLB | |
| SCHEMBL31560169 | 0.74 | KMT2A (0.50) | KMT2APOLB | |
| SCHEMBL16732 | 0.74 | KMT2A (0.50) | KMT2APOLB | |
| SCHEMBL10402003 | 0.74 | KMT2A (0.50) | KMT2ACA2CA12CA1CA9 | |
| SCHEMBL5421377 | 0.74 | KMT2A (0.50) | KMT2APOLB | |
| SCHEMBL4802533 | 0.73 | CA2 (0.53) | CA2CA12CA1CA9CA7 | |
| SCHEMBL10534768 | 0.73 | KMT2A (0.48) | KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996588-A1 | NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS | Torrent Pharmaceuticals Ltd (IN) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007100295-A1 | NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS | TORRENT PHARMACEUTICALS LTD (IN) | 2007-09-07 | — | — | WO | disclosed |