Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947328 | 0.96 | HSD17B10 (0.44) | HSD17B10MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL4762404 | 0.91 | BRD4 (0.42) | HSD17B10MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL4792215 | 0.91 | DYRK1A (0.40) | HSD17B10MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL3944372 | 0.87 | BRD4 (0.44) | HSD17B10MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL3947584 | 0.87 | BRD4 (0.48) | MAPTPOLBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3951262 | 0.86 | BRD4 (0.43) | HSD17B10MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL4762569 | 0.84 | ALDH1A1 (0.55) | MAPTPOLBSMN1; SMN2BACE1LMNA | |
| SCHEMBL3945495 | 0.84 | HSD17B10 (0.47) | HSD17B10MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL3950597 | 0.83 | BRD4 (0.42) | POLBSMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL3941796 | 0.83 | BRD4 (0.43) | MAPTPOLBSMN1; SMN2BACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001843-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2007107384-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | claimed |
| EP-2001843-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107384-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | disclosed |