Dimethylamine

Dimethylamine

SCHEMBL4762229

CC(CCOC(=O)c1sc(-c2ccccc2)nc1C)=C(F)F.CNC

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 8/20 0.53
MAPT P10636 6/20 0.53
ALDH1A1 P00352 5/20 0.53
GAA P10253 2/20 0.53
HPGD P15428 4/20 0.52
NPSR1 Q6W5P4 1/20 0.52
NPC1 O15118 7/20 0.51
CDC7 O00311 3/20 0.51
DBF4 Q9UBU7 3/20 0.51
TRPM8 Q7Z2W7 2/20 0.51
RAB9A P51151 7/20 0.49
CYP1A2 P05177 3/20 0.49
CYP2C19 P33261 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2D6 P10635 1/20 0.49
TSHR P16473 1/20 0.48
CYP3A4 P08684 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4767637 0.98 SMN1; SMN2 (0.54) SMN1; SMN2MAPTALDH1A1GAAHPGD
SCHEMBL4767289 0.90 SMN1; SMN2 (0.51) SMN1; SMN2MAPTALDH1A1GAAHPGD
SCHEMBL4772749 0.87 CDC7 (0.51) SMN1; SMN2MAPTALDH1A1GAANPC1
SCHEMBL4765999 0.87 SMN1; SMN2 (0.48) SMN1; SMN2MAPTALDH1A1GAAHPGD
SCHEMBL4771024 0.86 CDC7 (0.48) SMN1; SMN2MAPTALDH1A1GAAHPGD
SCHEMBL4762227 0.85 CDC7 (0.49) SMN1; SMN2MAPTALDH1A1GAANPC1
SCHEMBL4769034 0.85 MAPT (0.58) SMN1; SMN2MAPTALDH1A1GAAHPGD
SCHEMBL4767473 0.84 CDC7 (0.48) SMN1; SMN2MAPTALDH1A1GAANPC1
SCHEMBL4764983 0.83 RAB9A (0.58) SMN1; SMN2MAPTALDH1A1GAACDC7
SCHEMBL4763261 0.81 MAPT (0.69) SMN1; SMN2MAPTALDH1A1HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1439169-B1 DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO (JP) 2008-08-06 EP disclosed
EP-1439169-A1 DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-07-21 EP disclosed