SCHEMBL476295

SCHEMBL476295

CCCCc1nsc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 1/20 0.44
ACHE P22303 1/20 0.44
PTPN1 P18031 1/20 0.39
EPAS1 Q99814 4/20 0.39
GRM4 Q14833 2/20 0.38
CMA1 P23946 1/20 0.37
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
PARP1 P09874 1/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
IDO1 P14902 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28856577 0.93 ACHE (0.42) MAPTKDM4EALDH1A1HSD17B10ACHE
SCHEMBL28202495 0.89 KDM4E (0.47) MAPTKDM4EALDH1A1HSD17B10ACHE
SCHEMBL7435913 0.82 KDM4E (0.44) MAPTKDM4EALDH1A1HSD17B10ACHE
SCHEMBL8371416 0.81 MAPT (0.50) MAPTKDM4EALDH1A1HSD17B10ACHE
SCHEMBL31561724 0.78 KDM4E (0.47) MAPTKDM4EALDH1A1HSD17B10ACHE
SCHEMBL31556099 0.78 KDM4E (0.52) MAPTKDM4EALDH1A1HSD17B10ACHE
SCHEMBL5331835 0.77 ACHE (0.60) ACHEHRH3
SCHEMBL7432743 0.77 CMA1 (0.54) MAPTKDM4EALDH1A1HSD17B10ACHE
SCHEMBL5331281 0.75 ACHE (0.61) ACHEHRH3
SCHEMBL3874767 0.75 TP53 (0.43) KDM4EACHECMA1GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117305008-A Water-based die casting release agent and preparation method thereof 武汉优米克新材料有限公司 2023-12-29 CN claimed
CN-117186977-A Environment-friendly roller grinding fluid and preparation method thereof 武汉优米克新材料有限公司 2023-12-08 CN claimed
CN-108882706-A For the lenacil compound of dry film protection and the synergistic combination of N- butyl -1,2- benzisothiazole-3-ketone 陶氏环球技术有限责任公司 2018-11-23 CN claimed
CN-100509377-C Treated textiles and compositions for treating textiles MILLIKEN & CO (US) 2009-07-08 CN claimed
US-20060217279-A1 Surface treatment compositions for foaming process RISING LARRY 2006-09-28 US claimed
US-20060135386-A1 Chemical composition for a fire retardant textile RISING LARRY 2006-06-22 US claimed
US-20060035798-A1 Non-aqueous water and oil repellent compositions for a durable hydrophobic textile RISING LARRY 2006-02-16 US claimed
US-20050062010-A1 Treated textiles and compositions for treating textiles SAGE AUTOMOTIVE INTERIORS, INC. 2005-03-24 US claimed
CN-119372011-A Full-synthetic grinding fluid 南京科润工业介质股份有限公司 2025-01-28 CN disclosed
CN-117305008-A Water-based die casting release agent and preparation method thereof 武汉优米克新材料有限公司 2023-12-29 CN disclosed
CN-117186977-A Environment-friendly roller grinding fluid and preparation method thereof 武汉优米克新材料有限公司 2023-12-08 CN disclosed
US-11826992-B2 Composite structure JIVA MATERIALS LTD 2023-11-28 US disclosed
CN-114381141-A High washing fastness nano liquid disperse dye and preparation method and application thereof 张家港保税区亚诺化工有限公司 2022-04-22 CN disclosed
EP-3071038-B1 ENHANCED PRESERVATIVE ARCH CHEM INC (US) 2021-12-15 EP disclosed
EP-2411140-A1 PREPARATION OF SHAPED METAL PARTICLES AND THEIR USES BASF SE (DE) 2012-02-01 EP disclosed
EP-1550691-B1 Biocidal plastic material LUCITE INT UK LTD (GB) 2011-05-25 EP disclosed
WO-2010108837-A1 PREPARATION OF SHAPED METAL PARTICLES AND THEIR USES BASF SE (DE) 2010-09-30 WO disclosed
US-20060230576-A1 Sanitary handle-cover systems MEINE SHAWN 2006-10-19 US disclosed
EP-1550691-A1 Biocidal plastic material Lucite International UK Limited (GB) 2005-07-06 EP disclosed
US-6632855-B1 Useful as a component of a refrigerator, worktop etc. or as a building material LUCITE INTERNATIONAL UK LIMITED (GB) 2003-10-14 US disclosed