Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545018 | 0.83 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3GBA1GRM2 | |
| SCHEMBL30174437 | 0.83 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3GBA1GRM2 | |
| SCHEMBL27397592 | 0.79 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL3636577 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3GBA1GRM2 | |
| SCHEMBL31372524 | 0.74 | RAB9A (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19493715 | 0.74 | RAB9A (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2042093 | 0.74 | RAB9A (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28263198 | 0.73 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| Water SCHEMBL28259876 | 0.73 | RAB9A (0.49) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11249479 | 0.71 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968587-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | Coley Pharmaceutical, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007075468-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-05 | — | — | WO | disclosed |