Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPLP1 | P05386 | 4/20 | 0.37 |
| ▸ | RPLP0 | P05388 | 4/20 | 0.37 |
| ▸ | RPS17 | P08708 | 4/20 | 0.37 |
| ▸ | RPSA | P08865 | 4/20 | 0.37 |
| ▸ | RPS2 | P15880 | 4/20 | 0.37 |
| ▸ | RPL35A | P18077 | 4/20 | 0.37 |
| ▸ | RPL7 | P18124 | 4/20 | 0.37 |
| ▸ | RPL17 | P18621 | 4/20 | 0.37 |
| ▸ | RPS4Y1 | P22090 | 4/20 | 0.37 |
| ▸ | RPS3 | P23396 | 4/20 | 0.37 |
| ▸ | RPS12 | P25398 | 4/20 | 0.37 |
| ▸ | RPL13 | P26373 | 4/20 | 0.37 |
| ▸ | RPL10 | P27635 | 4/20 | 0.37 |
| ▸ | RPL12 | P30050 | 4/20 | 0.37 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 4/20 | 0.37 |
| ▸ | RPL22 | P35268 | 4/20 | 0.37 |
| ▸ | RPL4 | P36578 | 4/20 | 0.37 |
| ▸ | RPS19 | P39019 | 4/20 | 0.37 |
| ▸ | RPL3 | P39023 | 4/20 | 0.37 |
| ▸ | RPL13A | P40429 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593533 | 0.91 | RPLP1 (0.37) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4765366 | 0.86 | PSEN1 (0.33) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4763307 | 0.85 | PSEN1 (0.32) | — | |
| SCHEMBL4763252 | 0.82 | — | — | |
| SCHEMBL4767034 | 0.82 | RPLP1 (0.34) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL6593527 | 0.81 | RPLP1 (0.36) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL6591183 | 0.81 | CTSK (0.33) | — | |
| SCHEMBL4767021 | 0.80 | — | — | |
| SCHEMBL6591386 | 0.80 | PSEN1 (0.36) | — | |
| SCHEMBL4767027 | 0.80 | PSEN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320370-A4 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1320370-A1 | METHOD OF TREATMENT | SmithKline Beecham Corporation (US) | 2003-06-25 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002017924-A1 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORPORATION (GB) | 2002-03-07 | — | — | WO | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |