Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512467 | 0.86 | POLB (0.57) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1552759 | 0.85 | POLB (0.64) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1552760 | 0.85 | POLB (0.64) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4520942 | 0.84 | POLB (0.63) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6558080 | 0.84 | POLB (0.52) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6558090 | 0.84 | POLB (0.52) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30828600 | 0.73 | MAPT (0.67) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1553245 | 0.73 | POLB (0.63) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3416255 | 0.72 | POLB (0.62) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14735881 | 0.72 | HCAR3 (0.57) | MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934181-A2 | KINASE INHIBITORS | Devgen NV (BE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042321-A2 | KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-04-19 | — | — | WO | disclosed |