Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765287 | 0.95 | ADORA2A (0.42) | NCOA1NCOA3NPC1RAB9AADORA2A | |
| SCHEMBL4766274 | 0.95 | NPC1 (0.41) | NCOA1NCOA3NPC1RAB9AADORA2A | |
| SCHEMBL4767902 | 0.94 | NCOA1 (0.42) | NCOA1NCOA3NPC1RAB9AADORA2A | |
| SCHEMBL4767911 | 0.94 | NCOA1 (0.42) | NCOA1NCOA3NPC1RAB9AADORA2A | |
| SCHEMBL4765291 | 0.91 | NPC1 (0.40) | NCOA1NCOA3NPC1RAB9AADORA2A | |
| SCHEMBL4769586 | 0.88 | NCOA1 (0.39) | NCOA1NCOA3NPC1RAB9AADORA2A | |
| SCHEMBL4769599 | 0.88 | NCOA1 (0.39) | NCOA1NCOA3NPC1RAB9AADORA2A | |
| SCHEMBL4769729 | 0.87 | NCOA1 (0.44) | NCOA1NCOA3ADORA2AADORA2BMAPT | |
| SCHEMBL4763478 | 0.87 | NCOA1 (0.42) | NCOA1NCOA3NPC1RAB9AADORA2A | |
| SCHEMBL4763471 | 0.87 | NCOA1 (0.42) | NCOA1NCOA3NPC1RAB9AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-B1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-12-31 | — | — | EP | disclosed |