Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531819 | 0.81 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL12535906 | 0.81 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL2386978 | 0.81 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL12338477 | 0.81 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9597093 | 0.78 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9965992 | 0.78 | TP53 (0.51) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3716611 | 0.78 | MAPT (0.52) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9570044 | 0.78 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL14131227 | 0.77 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL12631459 | 0.77 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115624957-B | Modified functional silica gel material and preparation method and application thereof | 苏州硒诺唯新新材料科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115624957-A | Modified functional silica gel material and preparation method and application thereof | 苏州硒诺唯新新材料科技有限公司 | 2023-01-20 | — | — | CN | disclosed |
| EP-1979343-A2 | BICYCLIC HETEROARYL COMPOUNDS AS PDE10 INHIBITORS | Pfizer Products Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007077490-A2 | BICYCLIC HETEROARYL COMPOUNDS AS PDE10 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155779-A1 | BICYCLIC HETEROARYL COMPOUNDS AS PDE10 INHIBITORS | PFIZER INC | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155779-A1 | BICYCLIC HETEROARYL COMPOUNDS AS PDE10 INHIBITORS | PDE12, PDE10A, PDE7A | NPC1 1991/4885RAB9A 334/4885SMN1; SMN2 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.