SCHEMBL4765047

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL187741	0.85	KDR (0.57)	KDRCITMAP3K7RIPK2STK10
	SCHEMBL3960750	0.83	KDR (0.44)	KDRCITMAP3K7RIPK2STK10
	SCHEMBL447069	0.83	ATM (0.52)	MAPTMEN1KMT2AALDH1A1RAB9A
	SCHEMBL4767636	0.82	KDR (0.64)	KDRCITMAP3K7RIPK2STK10
	SCHEMBL16017748	0.82	KDR (0.57)	KDRCITMAP3K7RIPK2STK10
	SCHEMBL4775081	0.80	KDR (0.49)	KDRCITMAP3K7RIPK2STK10
	SCHEMBL4770524	0.79	KDR (0.40)	KDRCITMAP3K7RIPK2STK10
	SCHEMBL449576	0.79	KDR (0.67)	KDRCITMAP3K7RIPK2STK10
	SCHEMBL5428248	0.79	NOTUM (0.45)	KDRCITMAP3K7RIPK2STK10
	SCHEMBL5425124	0.79	PRKCI (0.49)	KDRCITMAP3K7RIPK2STK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.