Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.70 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.46 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881648 | 1.00 | HRH3 (0.70) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2886245 | 1.00 | HRH3 (0.70) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2878841 | 0.88 | HRH3 (0.57) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2886402 | 0.88 | HRH3 (0.57) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2887544 | 0.87 | HRH3 (0.54) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2879601 | 0.87 | HRH3 (0.54) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2885504 | 0.87 | HRH3 (0.54) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL1811575 | 0.82 | HRH3 (1.00) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL2883971 | 0.82 | HRH3 (0.65) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2884052 | 0.82 | HRH3 (0.65) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994022-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-11-26 | — | — | EP | claimed |
| WO-2007108936-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-09-27 | — | — | WO | claimed |