Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.42 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887544 | 1.00 | HRH3 (0.54) | HRH3L3MBTL3L3MBTL1HPGDMBTD1 | |
| SCHEMBL2885504 | 1.00 | HRH3 (0.54) | HRH3L3MBTL3L3MBTL1HPGDMBTD1 | |
| SCHEMBL2878841 | 0.94 | HRH3 (0.57) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2886402 | 0.94 | HRH3 (0.57) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5483868 | 0.92 | HPGD (0.48) | HRH3L3MBTL3L3MBTL1HPGDPKM | |
| SCHEMBL2881648 | 0.87 | HRH3 (0.70) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2886245 | 0.87 | HRH3 (0.70) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4765310 | 0.87 | HRH3 (0.70) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2879242 | 0.86 | KDM1A (0.45) | HRH3HPGDPKMSMN1; SMN2 | |
| SCHEMBL2883891 | 0.86 | KDM1A (0.45) | HRH3HPGDPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820825-B2 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH LLC (US) | 2010-10-26 | — | — | US | claimed |
| US-20070219240-A1 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH (US) | 2007-09-20 | — | — | US | claimed |
| US-7820825-B2 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH LLC (US) | 2010-10-26 | — | — | US | disclosed |
| US-20070219240-A1 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219240-A1 | N-substituted-azacyclylamines as histamine-3 antagonists | HNMT, HRH4, HRH3 | HRH3 3/4885L3MBTL3 3550/4885L3MBTL1 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.