Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.55 |
| ▸ | NAMPT | P43490 | 11/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4764947 | 0.86 | HRH3 (0.56) | HRH3NAMPTCYP2D6 | |
| SCHEMBL4771923 | 0.84 | HRH3 (0.48) | HRH3NAMPTEPHX2CYP2D6 | |
| SCHEMBL4765338 | 0.83 | HRH3 (0.56) | HRH3NAMPTEPHX2CYP2D6 | |
| SCHEMBL4767933 | 0.82 | RAB9A (0.52) | HRH3NAMPTCYP2D6 | |
| SCHEMBL4768450 | 0.80 | HRH3 (0.57) | HRH3CYP2D6 | |
| SCHEMBL4774355 | 0.80 | HRH3 (0.57) | HRH3NAMPTCYP2D6 | |
| SCHEMBL4771050 | 0.80 | CYP3A4 (0.56) | HRH3NAMPTCYP2D6 | |
| SCHEMBL4767666 | 0.79 | CYP3A4 (0.58) | HRH3NAMPTCYP2D6 | |
| SCHEMBL4767921 | 0.79 | NPC1 (0.56) | HRH3NAMPTCYP2D6 | |
| SCHEMBL5823896 | 0.78 | HRH3 (0.54) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | claimed |
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | HRH3, HRH4, HRH1 | HRH3 1/4885NAMPT 2325/4885EPHX2 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.