Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678963 | 0.90 | SLC6A9 (1.00) | SLC6A9CYP2C9 | |
| SCHEMBL23815795 | 0.90 | SLC6A9 (1.00) | SLC6A9CYP2C9 | |
| SCHEMBL4719141 | 0.88 | SLC6A9 (0.64) | SLC6A9CYP2C9 | |
| SCHEMBL3548889 | 0.82 | SLC6A9 (1.00) | SLC6A9CYP2C9 | |
| SCHEMBL4722322 | 0.82 | SLC6A9 (0.56) | SLC6A9CYP2C9 | |
| SCHEMBL26840799 | 0.80 | SLC6A9 (0.82) | SLC6A9CYP2C9 | |
| SCHEMBL678955 | 0.80 | SLC6A9 (0.82) | SLC6A9CYP2C9 | |
| SCHEMBL4371990 | 0.80 | SLC6A9 (0.82) | SLC6A9CYP2C9 | |
| SCHEMBL4370555 | 0.80 | SLC6A9 (0.82) | SLC6A9CYP2C9 | |
| SCHEMBL4366696 | 0.80 | SLC6A9 (0.82) | SLC6A9CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891002-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | Merck Sharp & Dohme Limited (GB) | 2008-02-27 | — | — | EP | claimed |
| WO-2006131713-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | MERCK SHARP & DOHME LIMITED (GB) | 2006-12-14 | — | — | WO | claimed |
| EP-1893566-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | MERCK SHARP & DOHME LTD. (GB) | 2008-03-05 | — | — | EP | disclosed |
| EP-1891002-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | Merck Sharp & Dohme Limited (GB) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006131711-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | MERCK SHARP & DOHME LIMITED (GB) | 2006-12-14 | — | — | WO | disclosed |
| WO-2006131713-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | MERCK SHARP & DOHME LIMITED (GB) | 2006-12-14 | — | — | WO | disclosed |