SCHEMBL476606

SCHEMBL476606

C=C(C)C(=O)OCCC[Si](Cl)(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
THRB P10828 1/20 0.48
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477794 0.96 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2779393 0.94 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4846356 0.93 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321578 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321961 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321664 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321652 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321771 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321999 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23322077 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2210 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059985-A Methacryloxypropyl triacetyl preparation method of oxo silane 山东硅科新材料有限公司 2026-05-19 CN claimed
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
EP-3966881-B1 LITHIUM-ION BATTERY SEPARATOR COATED WITH SURFACE TREATED ALUMINA EVONIK OPERATIONS GMBH (DE) 2026-03-18 EP claimed
CN-121571356-A Environment-friendly emission-reducing type vehicle tail gas exhaust pipe and preparation process thereof 扬州翰昇汽车配件有限公司 2026-02-27 CN claimed
CN-121574311-A Honeycomb rigid-flexible two-phase particles and application thereof in photocuring 3d printing resin 西南交通大学 2026-02-27 CN claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
CN-119015494-A Low-modulus modified bone cement and preparation method thereof 上海朗迈医疗器械科技有限公司 2024-11-26 CN claimed
WO-2024180279-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF PIBOND OY (FI) 2024-09-06 WO claimed
CN-118341658-A Preparation method and application of hydrogel coating 海宁德迈生物科技有限公司 2024-07-16 CN claimed
CN-118292133-A Preparation method of antibacterial polypropylene colored fiber 万华化学(宁波)有限公司 2024-07-05 CN claimed
US-5110439-A Capillary gel column with polyorganosiloxane coupling layer HEWLETT-PACKARD COMPANY (US) 1992-05-05 US claimed
US-5103032-A Polymerization inhibition during distillation UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-04-07 US claimed
WO-1991019606-A1 METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER ADVANCED GLASS TREATMENT SYSTEMS (US) 1991-12-26 WO claimed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed
US-4924022-A Method for preparation of organoalkoxysilanes DOW CORNING CORPORATION (US) 1990-05-08 US claimed
EP-0311348-A2 Novel macromers containing a polyether moiety, process of preparing them and polymers thereof Nippon Oil Co., Ltd. (JP) 1989-04-12 EP claimed
US-4780555-A USING PLATINUM HYDROSILATION CATALYST AND PHENOTHIAZINE DOW CORNING CORPORATION (US) 1988-10-25 US claimed
US-4506087-A Method for the continuous preparation of alkoxysilanes DYNAMIT NOBEL AG (DE) 1985-03-19 US claimed
EP-0067909-A1 Oxygen permeable hard and semi-hard contact lens compositions, processes for their preparation, contact lenses and their manufacture from such compositions SYNTEX (U.S.A.) INC. (US) 1982-12-29 EP claimed
US-4242483-A FROM AN UNSATURATED SILICON CONTAINING MONOMER AND AN ACRYLIC OR METHACRYLIC ESTER OR ITACONATE ESTER SYNTEX OPHTHALMICS, INC., 1980-12-30 US claimed