Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652309 | 0.93 | THRB (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4849126 | 0.93 | THRB (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL476606 | 0.93 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15477794 | 0.90 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2779393 | 0.88 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321961 | 0.86 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321578 | 0.86 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321966 | 0.86 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321999 | 0.86 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321664 | 0.86 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317117-B2 | Siloxanyl-containing monomers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| EP-1354898-B1 | MONOMER COMPOSITION, POLYMER OBTAINED THEREFROM, AND OCULAR LENS | JOHNSON & JOHNSON VISION CARE (US) | 2006-04-26 | — | — | EP | disclosed |
| US-20060012750-A1 | Monomer composition and polysmers and ophthalmic lenses in which it is used | JOHNSON & JOHNSON VISION CARE, INC. | 2006-01-19 | — | — | US | disclosed |
| US-20040249180-A1 | Monomer, polymer, and ocular lens comprising the same | JOHNSON & JOHNSON VISION CARE, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1439181-A1 | MONOMER, POLYMER, AND OCULAR LENS COMPRISING THE SAME | Johnson & Johnson Vision Care, Inc. (US) | 2004-07-21 | — | — | EP | disclosed |
| EP-1354898-A1 | MONOMER COMPOSITION, POLYMER OBTAINED THEREFROM, AND OCULAR LENS | Johnson & Johnson Vision Care, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249180-A1 | Monomer, polymer, and ocular lens comprising the same | CRYAA, SMCHD1, NAP1L1 | TSHR 4554/4885THRB 4608/4885POLB 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.