Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431770 | 0.87 | NCF1 (0.54) | RAB9ANPC1SMN1; SMN2NCF1CYP1A2 | |
| SCHEMBL27665935 | 0.83 | PDGFRB (0.49) | MEN1KMT2ABRAFSRCTGFBR1 | |
| SCHEMBL7458619 | 0.82 | APP (0.52) | MEN1NPC1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL4472632 | 0.79 | KDM4E (0.43) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL1591720 | 0.79 | NCF1 (0.56) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL12386844 | 0.78 | KDR (0.48) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL828159 | 0.77 | GAK (0.55) | SMN1; SMN2NCF1LOXL2BRAFRIPK2 | |
| SCHEMBL22972146 | 0.77 | SRC (0.45) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL13836171 | 0.77 | GAK (0.49) | RAB9ANPC1TSHRSMN1; SMN2NCF1 | |
| SCHEMBL1897179 | 0.77 | ERBB2 (0.55) | KMT2ANCF1LOXL2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122212-A1 | TGF-BETA PATHWAY INHIBITORS FOR ENHANCEMENT OF CELLULAR REPROGRAMMING OF HUMAN CELLS | IPIERIAN, INC. | 2012-05-17 | — | — | US | disclosed |