Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435526 | 1.00 | CTSK (0.49) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL5451133 | 1.00 | CTSK (0.49) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL23845173 | 0.98 | CTSK (0.50) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL5416784 | 0.98 | CTSK (0.50) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL13287349 | 0.98 | CTSK (0.50) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL13399539 | 0.92 | CTSK (0.46) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL19982034 | 0.86 | CTSK (0.62) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL16709994 | 0.86 | CTSK (0.62) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL27610791 | 0.86 | CTSK (0.62) | CTSKCTSLCTSBHRH2HRH1 | |
| SCHEMBL4180221 | 0.85 | HRH2 (0.49) | CTSKCTSLCTSBHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | disclosed |