Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.47 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4108238 | 0.99 | CYP24A1 (0.46) | CYP24A1CYP27A1ACHEGPR84MPO | |
| SCHEMBL4766578 | 0.91 | ACHE (0.43) | CYP24A1CYP27A1ACHEGPR84MPO | |
| Hydrochloric Acid SCHEMBL4097040 | 0.90 | ACHE (0.42) | CYP24A1CYP27A1ACHEGPR84MPO | |
| SCHEMBL4762824 | 0.88 | ACHE (0.41) | CYP24A1CYP27A1ACHEGPR84MPO | |
| SCHEMBL4766814 | 0.88 | ACHE (0.42) | CYP24A1CYP27A1ACHEGPR84MPO | |
| SCHEMBL4763011 | 0.87 | ACHE (0.41) | CYP24A1CYP27A1ACHEGPR84MPO | |
| SCHEMBL4770996 | 0.87 | ACHE (0.41) | CYP24A1CYP27A1ACHEGPR84MPO | |
| Hydrochloric Acid SCHEMBL4101729 | 0.87 | ACHE (0.41) | CYP24A1CYP27A1ACHEGPR84MPO | |
| Hydrochloric Acid SCHEMBL4103791 | 0.87 | ACHE (0.42) | CYP24A1CYP27A1ACHEGPR84MPO | |
| Hydrochloric Acid SCHEMBL4097920 | 0.87 | ACHE (0.40) | CYP24A1CYP27A1ACHEGPR84MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896419-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVES | HANWHA CHEMICAL CORPORATION (KR) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006129978-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVES | HANWHA CHEMICAL CORPORATION (KR) | 2006-12-07 | — | — | WO | disclosed |