Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 12/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932523 | 1.00 | RXFP1 (0.73) | RXFP1PTGS1GAAALDH1A1LMNA | |
| SCHEMBL29085612 | 0.89 | RXFP1 (0.67) | RXFP1PTGS1GAAALDH1A1P2RX1 | |
| SCHEMBL15775396 | 0.86 | PTGS1 (0.68) | RXFP1PTGS1 | |
| SCHEMBL6720875 | 0.85 | MEN1 (0.73) | ALDH1A1LMNA | |
| SCHEMBL15530200 | 0.84 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL30112566 | 0.82 | RXFP1 (0.79) | RXFP1 | |
| SCHEMBL28473857 | 0.82 | RXFP1 (0.79) | RXFP1 | |
| SCHEMBL28633823 | 0.82 | PTGS1 (0.72) | RXFP1PTGS1GAAALDH1A1LMNA | |
| SCHEMBL11868617 | 0.82 | PTGS1 (0.72) | RXFP1PTGS1GAAALDH1A1LMNA | |
| SCHEMBL30136206 | 0.82 | PTGS1 (0.72) | RXFP1PTGS1GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779078-A | New inhibitor and probe of kinases and application thereof | 北京大学深圳研究生院 | 2018-11-09 | — | — | CN | disclosed |
| EP-1928844-A2 | BIS-ARYL AMIDE COMPOUNDS AND METHODS OF USE | Amgen, Inc (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007022380-A2 | BIS-ARYL AMIDE COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2007-02-22 | — | — | WO | disclosed |